L'industrie pharmaceutique est contrainte de revoir sa stratégie
Yves Mamou,
Le Monde, February 1st, 2005

"Outre
l'industrie du générique qui grignote les brevets
existants, le secteur souffre aujourd'hui d'une grave crise de
productivité de sa recherche : les nouveaux produits manquent
qui pourraient remplacer les plus anciens."
Human element: drug industry's big push into technology falls short

"Last
year, the U.S. FDA approved only 21 new drugs, marking a steady decline
since a peak of 53 in 1996. Many of the world's largest drug companies
failed to win U.S. approval for a single new drug in 2003."

"Many
observers believe the introduction of new technology in the 1990s helps
to explain today's drought of new drugs, which take years between
discovery and approval. "Ten years later, we're seeing the effects. The
output has decreased tremendously."
Fixing the Drug Pipeline

"The underlying
challenge [...] is to address the innovation deficit. But how? Flashy
new drug-discovery technology has lost its shine, having consumed huge
sums of money during the 1990s with little to show for it. Yet
something new is undoubtedly needed."