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Document center - The pipeline challenge

L'industrie pharmaceutique est contrainte de revoir sa stratégie
Yves Mamou, Le Monde, February 1st, 2005
"Outre l'industrie du générique qui grignote les brevets existants, le secteur souffre aujourd'hui d'une grave crise de productivité de sa recherche : les nouveaux produits manquent qui pourraient remplacer les plus anciens."

Human element: drug industry's big push into technology falls short
Peter Landers, The Wall Street Journal, February 24, 2004
 "Last year, the U.S. FDA approved only 21 new drugs, marking a steady decline since a peak of 53 in 1996. Many of the world's largest drug companies failed to win U.S. approval for a single new drug in 2003."
 "Many observers believe the introduction of new technology in the 1990s helps to explain today's drought of new drugs, which take years between discovery and approval. "Ten years later, we're seeing the effects. The output has decreased tremendously."

Fixing the Drug Pipeline
The Economist, vol. 370, issue 8366, p37-38, March 13, 2004
 "The underlying challenge [...] is to address the innovation deficit. But how? Flashy new drug-discovery technology has lost its shine, having consumed huge sums of money during the 1990s with little to show for it. Yet something new is undoubtedly needed."
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